Apolipoprotein E alleles in women with severe pre-eclampsia.

Short reports Apolipoprotein E alleles in women with severe pre-eclampsia

This study investigated the frequency of apolipoprotein E (apoE) alleles among women with severe pre-eclampsia. The presence of the three most common apoE alleles (å2, å3, å4) was determined by polymerase chain reaction-restriction fragment length polymorphism in three groups of white women: non-pregnant healthy (n = 101), pregnant healthy (n = 52), and pregnant with a diagnosis of severe pre-e...

Association Of Maternal Hypothyroidism With Pre-eclampsia

  Background and Objective: Hypertensive disorders complicating pregnancy are common and from one of the deadly triad, along with hemorrhage and infection that contribute greatly to prenatal and maternal morbidity and mortality in the developing countries. This study was designed to investigate the relationship between maternal hypothyroidism and pre-eclampsia. Materials and Methods: In a pro...

Beta-Human Chorionic Gonadotropin (βHCG) Levels in Pre-eclamptic and Normotensive Pregnant Women

Background: Pre-eclampsia along with bleeding and infection constitute a triad that is a major cause of maternal mortality. Many factors have been recognized which can help us to determine the severity of the disease and early diagnosis of it. Since throphoblastic disorder is one of the etiological causes of pre-eclampsia, we decided to measure the level of β-hCG as a marker of detecting the ac...

Importance of Anti-GRP78 Antibody in Pre-Eclampsia

Background: Preeclampsia (PE) is a pregnancy specific syndrome that is associated with high maternal and fetal morbidity and mortality. Glucose regulated protein78 (GRP78) is an Endoplasmic Reticulum (ER) protein which is expressed on the cell surfaces of trophoblast cells under stress or hypoxic condition. GRP78 has a role in aggressive behavior of invasive cells and may play a role in normal ...

Frequency of Apolipoprotein E Alleles in Iranian Populations